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瞬态诱发耳声发射的对侧抑制:耳鸣患者与正常受试者的个体内变异性

Contralateral suppression of transient evoked otoacoustic emissions: intra-individual variability in tinnitus and normal subjects.

作者信息

Graham R L, Hazell J W

机构信息

RNID Medical Research Unit, ILO with the Ferens, University College, London, Middlesex Hospital, UK.

出版信息

Br J Audiol. 1994 Aug-Oct;28(4-5):235-45. doi: 10.3109/03005369409086573.

Abstract

Contralateral acoustic stimulation reduces the amplitude of the transient evoked otoacoustic emission (TEOAE) in humans. The mechanism is thought to be mediated, at least in part, through the medial olivocochlear efferent system innervating the outer hair cells. To assess its usefulness as a possible clinical test, TEOAE suppression was measured in each ear of 12 subjects over a 6-week period, and these data are shown in detail for four subjects representing extremes of variability in a tinnitus and a non-tinnitus group. Intra-subject test results (n = 18) exhibited a varying extent of suppression values and the variance of each session, consisting of three tests, was not statistically different from one session to another. There was no dependence on variables such as ear (right or left), session, day of testing or their interaction. There was a significant difference in the variability between the tinnitus and the normal group.

摘要

对侧听觉刺激可降低人类瞬态诱发耳声发射(TEOAE)的幅度。其机制被认为至少部分是通过支配外毛细胞的内侧橄榄耳蜗传出系统介导的。为评估其作为一种可能的临床测试的实用性,在6周时间内对12名受试者的每只耳朵进行了TEOAE抑制测量,并详细展示了代表耳鸣组和非耳鸣组变异性极端情况的4名受试者的数据。受试者内测试结果(n = 18)显示出不同程度的抑制值,且由三次测试组成的每个测试时段的方差在各时段之间无统计学差异。不存在对诸如耳朵(右耳或左耳)、测试时段、测试日期或它们之间相互作用等变量的依赖性。耳鸣组和正常组之间在变异性方面存在显著差异。

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