Nalin C M
Department of Oncology, Sandoz Research Institute, Sandoz Pharmaceuticals Corporation, East Hanover, NJ 07496, USA.
Structure. 1995 Feb 15;3(2):143-5. doi: 10.1016/s0969-2126(01)00144-7.
Recent elucidation of the structure of interleukin-1 beta-converting enzyme (ICE), a protease with sequence homology to a nematode protein associated with programmed cell death, opens a new chapter in the study of how proteases may control cellular suicide.
白细胞介素-1β转换酶(ICE)是一种蛋白酶,其序列与一种与程序性细胞死亡相关的线虫蛋白具有同源性,最近对其结构的阐明为研究蛋白酶如何控制细胞自杀开启了新篇章。