The interaction between halofenate and propranolol.
作者信息
Huffman D H, Azarnoff D L, Shoeman D W, Dujovne C A
出版信息
Clin Pharmacol Ther. 1976 Jun;19(6):807-12. doi: 10.1002/cpt1976196807.
PMID:773588
Abstract
The effect of halofenate on beta adrenergic blockade by propranolol was studied in 4 subjects during chronic drug administration in a randomized, double-blind study. The plasma propranolol concentration was significantly lower during treatment with halofenate than with placebo. The reduction in propranolol levels correlated with a decrease in beta adrenergic blockade. The mechanism for the decrease in plasma concentration has not been determined.
摘要
相似文献
1
The interaction between halofenate and propranolol.
Clin Pharmacol Ther. 1976 Jun;19(6):807-12. doi: 10.1002/cpt1976196807.
2
Potentiation of hypoglycemic effect of sulfonylureas by halofenate.
N Engl J Med. 1975 Dec 18;293(25):1283-6. doi: 10.1056/NEJM197512182932503.
3
Long-term efficacy of halofenate on serum triglyceride levels.
Curr Ther Res Clin Exp. 1975 Dec;18(6):855-61.
4
Halofenate. Its selection and trial as a primary uricosuric agent.
Arthritis Rheum. 1975 Nov-Dec;18(6 Suppl):859-62. doi: 10.1002/art.1780180732.
5
Comparison of the effects of halofenate (MK-185) and clofibrate on plasma lipid and uric acid concentration in hyperlipoproteinemic patients.
Atherosclerosis. 1975 May-Jun;21(3):391-9. doi: 10.1016/0021-9150(75)90051-9.
6
The metabolic spectrum of halofenate.
Int J Clin Pharmacol Biopharm. 1975 Jul;12(1-2):239-43.
7
Changes in serum thyrotropin (TSH) in man during halofenate administration.在人类服用卤芬酯期间血清促甲状腺激素（TSH）的变化。
J Clin Endocrinol Metab. 1976 Oct;43(4):873-81. doi: 10.1210/jcem-43-4-873.
8
Anomalous results of studies on drug interaction in man. II. Halofenate (mk-185) and antipyrine, bishydroxycoumarin, and warfarin.
Pharmacology. 1975;13(2):112-27. doi: 10.1159/000136892.
9
Effects of halofenate on glucose tolerance in patients with hyperlipoproteinemia.
J Clin Pharmacol. 1978 May-Jun;18(5-6):241-8. doi: 10.1002/j.1552-4604.1978.tb02442.x.
10
The effect of halofenate or halofenate free acid on human, rat and guinea pig platelet aggregation.
Thromb Haemost. 1976 Apr 30;35(2):358-63.
引用本文的文献
1
Effects of chlorpromazine on the disposition and beta-adrenergic blocking activity of propranolol in the dog.氯丙嗪对狗体内普萘洛尔的处置及β-肾上腺素能阻断活性的影响。
J Pharmacokinet Biopharm. 1984 Jun;12(3):333-49. doi: 10.1007/BF01061724.
2
Pharmacokinetic drug interactions with propranolol.普萘洛尔的药代动力学药物相互作用。
Clin Pharmacokinet. 1983 May-Jun;8(3):253-62. doi: 10.2165/00003088-198308030-00004.
3
Effect of halofenate on the serum binding of phenytoin.卤芬酯对苯妥英血清结合的影响。
Br J Clin Pharmacol. 1977 Oct;4(5):625-6. doi: 10.1111/j.1365-2125.1977.tb00798.x.
Zotero 插件