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Regional localization of the ovine NRAMP gene to chromosome 2q41-->q42 by in situ hybridization.

作者信息

Pitel F, Cribiu E P, Yerle M, Lahbib-Mansais Y, Lanneluc I, Lantier F, Gellin J

机构信息

Laboratoire de Génétique Cellulaire, INRA-CRT, Castanet-Tolosan, France.

出版信息

Cytogenet Cell Genet. 1995;70(1-2):116-8. doi: 10.1159/000134004.

DOI:10.1159/000134004
PMID:7736775
Abstract

The murine Ity/Lsh/Bcg locus belongs to a conserved region between mouse Chromosome 1 and human chromosome 2. This gene governs mouse resistance to several intracellular pathogens. We have localized the gene on sheep chromosome 2q41-->q42 by radioactive in situ hybridization using a 2.1-kb fragment of the ovine equivalent of this gene.

摘要

相似文献

1
Regional localization of the ovine NRAMP gene to chromosome 2q41-->q42 by in situ hybridization.
Cytogenet Cell Genet. 1995;70(1-2):116-8. doi: 10.1159/000134004.
2
Cloning, sequencing, and localization of an ovine fragment of the NRAMP gene, a candidate for the ITY/LSH/BCG gene.
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Nramp transfection transfers Ity/Lsh/Bcg-related pleiotropic effects on macrophage activation: influence on oxidative burst and nitric oxide pathways.Nramp转染传递Ity/Lsh/Bcg相关的多效性效应以影响巨噬细胞激活：对氧化爆发和一氧化氮途径的影响。
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Two polymorphic microsatellite markers close to the ovine NRAMP gene.
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Natural resistance to infection with intracellular parasites: molecular genetics identifies Nramp1 as the Bcg/Ity/Lsh locus.对细胞内寄生虫感染的天然抵抗力：分子遗传学将Nramp1鉴定为Bcg/Ity/Lsh基因座。
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Genetic and physical mapping of 2q35 in the region of the NRAMP and IL8R genes: identification of a polymorphic repeat in exon 2 of NRAMP.NRAMP和IL8R基因区域2q35的遗传与物理图谱构建：NRAMP基因外显子2中一个多态性重复序列的鉴定。
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Isolation and characterization of human Nramp cDNA.
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