脱氢表雄酮硫酸转移酶基因（STD）：定位于人类染色体19q13.3带。

Dehydroepiandrosterone sulfotransferase gene (STD): localization to human chromosome band 19q13.3.

作者信息

Otterness D M, Mohrenweiser H W, Brandriff B F, Weinshilboum R M

机构信息

Department of Pharmacology, Mayo Medical School/Mayo Clinic/Mayo Foundation, Rochester, MN 55905, USA.

出版信息

Cytogenet Cell Genet. 1995;70(1-2):45-7. doi: 10.1159/000133988.

DOI:10.1159/000133988

PMID:7736787

Abstract

Dehydroepiandrosterone (DHEA) sulfotransferase (ST) catalyzes the sulfate conjugation of DHEA and other steroid compounds. The human gene for DHEA ST (STD) was mapped by the polymerase chain reaction to chromosome 19 using human x rodent somatic cell hybrid panels. Fluorescence in situ hybridization was then used to localize the STD gene to the region 19q13.3.

摘要

脱氢表雄酮（DHEA）硫酸转移酶（ST）催化DHEA及其他类固醇化合物的硫酸结合反应。利用人-啮齿类体细胞杂交板，通过聚合酶链反应将人类DHEA ST（STD）基因定位于19号染色体。随后采用荧光原位杂交技术将STD基因定位到19q13.3区域。