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[慢性冠状动脉闭塞病变的再通:哪些因素影响成功率?]

[The recanalization of chronic coronary artery occlusions: what factors influence success?].

作者信息

Giokoglu K, Preusler W, Störger H, Hofmann M, Klöpper J W, Schwarz F, Reifart N

机构信息

Abteilung Kardiologie, Rotes-Kreuz-Krankenhaus, Frankfurt.

出版信息

Dtsch Med Wochenschr. 1994 Dec 23;119(51-52):1766-70. doi: 10.1055/s-2008-1058898.

Abstract

Between January 1986 and June 1990, recanalization with guide-wire and balloon angioplasty (PTCA) was attempted in 509 patients (416 men, 93 women; mean age 57.5 +/- 9 years) with chronic coronary artery occlusions. The data recorded were analysed to determine the factors which influenced the outcome. The intervention was initially successful in 284 patients (55.8%; circumflex branch: 50%; right coronary artery: 52%; venous bypass graft: 50%; anterior interventricular branch: 64%). The success rate was markedly reduced if (1) the occlusion had persisted for more than 6 months (9.5%; P < 0.001); (2) occlusion had occurred at or after a vessel kink (28.5%; P < 0.001); (3) there had been no vessel "stump" (36%; P < 0.01) and (4) the occlusion was longer than 10 mm (40.7%; P < 0.05). The success-rate was higher if (1) intracoronary anastomoses were absent (61.2%); (2) occlusion had occurred in a straight vessel (62.6%); (3) there had been a vessel stump (64%); (4) the occlusion had persisted for less than 4 weeks (68.5%) and (5) the length of occlusion was < or = 10 mm (75.8%).-These data indicate that the success of PTCA after chronic coronary artery occlusion depended on the site of occlusion, its duration and length, absence of orthograde collaterals and the presence of a vessel stump. Knowing the extent of these factors helps in delineating the indications.

摘要

1986年1月至1990年6月期间,对509例(416例男性,93例女性;平均年龄57.5±9岁)慢性冠状动脉闭塞患者尝试进行导丝再通及球囊血管成形术(PTCA)。对记录的数据进行分析以确定影响结果的因素。最初有284例患者(55.8%)干预成功(回旋支:50%;右冠状动脉:52%;静脉搭桥移植血管:50%;前室间支:64%)。如果出现以下情况,成功率会显著降低:(1)闭塞持续时间超过6个月(9.5%;P<0.001);(2)闭塞发生在血管扭曲处或之后(28.5%;P<0.001);(3)不存在血管“残端”(36%;P<0.01);(4)闭塞长度超过10mm(40.7%;P<0.05)。如果出现以下情况,成功率会更高:(1)不存在冠状动脉内吻合支(61.2%);(2)闭塞发生在直血管中(62.6%);(3)存在血管残端(64%);(4)闭塞持续时间少于4周(68.5%);(5)闭塞长度≤10mm(75.8%)。这些数据表明,慢性冠状动脉闭塞后PTCA的成功取决于闭塞部位、持续时间和长度、不存在正向侧支以及血管残端的存在。了解这些因素的程度有助于明确适应症。

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