Angibaud G, Moreau M S, Rascol O, Clanet M
Service de Neurologie et d'Explorations Fonctionnelles Neurologiques, Hôpital Purpan, Toulouse, France.
Eur Neurol. 1995;35(1):43-5. doi: 10.1159/000117088.
Thirty-two patients with hemifacial spasm were treated with 61 botulinum toxin (BT) injections. Some patients had post-BT lower facial paresis (LFP+group) while others did not suffer this side effect (LFP-group). Abnormal electromyography (EMG) recordings were more frequent in the LFP+ group (6/11) than in the LFP- group (3/21; p < 0.05). This result suggests that an EMG performed before any BT injection could detect the patients with a higher risk for this side effect. The first dose of BT might be lowered in such cases.
32例面肌痉挛患者接受了61次肉毒杆菌毒素（BT）注射治疗。部分患者出现了BT注射后的下半面部轻瘫（LFP+组），而其他患者未出现这种副作用（LFP-组）。LFP+组（6/11）异常肌电图（EMG）记录比LFP-组（3/21；p<0.05）更常见。这一结果表明，在任何BT注射前进行的肌电图检查可以检测出出现这种副作用风险较高的患者。在这种情况下，首剂BT剂量可能需要降低。
