家族性播散性非典型分枝杆菌病

Familial disseminated atypical mycobacterial disease.

作者信息

Newport M, Levin M

机构信息

Department of Paediatrics, St Mary's Hospital Medical School, Imperial College of Science, Technology and Medicine, London, UK.

出版信息

Immunol Lett. 1994 Dec;43(1-2):133-8. doi: 10.1016/0165-2478(94)00145-6.

DOI:10.1016/0165-2478(94)00145-6

PMID:7737683

Abstract

Mycobacterial disease remains a major public health problem and there appears to be a genetic component underlying susceptibility. This paper describes a group of related children who appear to have a genetic predisposition to disseminated atypical mycobacterial infection. Identification of the defect in this group could lead to better understanding of the genetics of susceptibility to mycobacterial infection.

摘要

分枝杆菌病仍然是一个主要的公共卫生问题，而且易感性背后似乎存在遗传因素。本文描述了一组相关儿童，他们似乎对播散性非典型分枝杆菌感染具有遗传易感性。确定该组中的缺陷可能有助于更好地理解分枝杆菌感染易感性的遗传学。