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[高密度聚焦超声治疗难治性青光眼]

[Treatment of refractory glaucoma with high density focused ultrasonics].

作者信息

Valtot F, Kopel J, Petit E, Moulin F, Haut J

机构信息

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris.

出版信息

J Fr Ophtalmol. 1995;18(1):3-12.

PMID:7738293
Abstract

The efficacy of therapeutic ultrasound was retrospectively assessed in 456 patients who presented with uncontrolled glaucoma refractory to maximal medical therapy and filtration surgery from April 1987 to January 1992. Treatment was performed under local anaesthesia in ambulatory outpatients. Therapeutic ultrasound induced local destruction of the ciliary epithelium and a thickening of the sclera. A 47% decrease in intraocular pressure (IOP) was obtained from the mean preoperative (33.8 mmHg) and the mean postoperative (18.2 mm Hg) values. After a 33-month mean follow-up, 65% of treated eyes had an IOP less than or egal to 20 mmHg. Therapeutic ultrasound was effective in most of the glaucomas, especially in open angle, closed angle, aphakic, pseudophakic and post-silicone oil glaucoma. The main complications were immediate ocular hypertension and corneoscleral alterations. Phtysis bulbi occurred in 5.7% of the eyes. The therapeutic interest of ultrasound were compared with those of the other cyclodestruction techniques.

摘要

1987年4月至1992年1月期间,对456例接受最大药物治疗和滤过手术仍无法控制的难治性青光眼患者进行了治疗性超声疗效的回顾性评估。治疗在门诊患者的局部麻醉下进行。治疗性超声引起睫状体上皮局部破坏和巩膜增厚。眼内压(IOP)从术前平均(33.8 mmHg)降至术后平均(18.2 mmHg),降幅为47%。平均随访33个月后,65%的治疗眼眼压低于或等于20 mmHg。治疗性超声对大多数青光眼有效,尤其是开角型、闭角型、无晶状体眼、人工晶状体眼和硅油填充后青光眼。主要并发症为即刻高眼压和角巩膜改变。眼球萎缩发生在5.7%的眼中。将超声的治疗价值与其他睫状体破坏技术的治疗价值进行了比较。

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J Fr Ophtalmol. 1995;18(1):3-12.
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BME Front. 2022 Jun 8;2022:9840678. doi: 10.34133/2022/9840678. eCollection 2022.
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Efficacy and safety of high-dose ultrasound cyclo-plasty procedure in refractory glaucoma.高剂量超声睫状体成形术治疗难治性青光眼的疗效与安全性
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