Yamazumi R, Kobayashi H, Horie T, Asano R, Momose M, Kusakabe K, Hosoda S
Heart Institute of Japan, Tokyo Women's Medical College.
Kaku Igaku. 1995 Mar;32(3):271-9.
We have often experienced false positive results of the stress Thallium-201 myocardial scintigraphy (TL) for the evaluation of artery bypass graft patency after coronary artery bypass surgery (CABG). The purpose of this study is to clarify the frequency and the clinical significance of this findings. Sixty-two patients undergoing coronary angiography (CAG) after CABG were studied. These patients had undergone at total of 156 bypasses (artery grafts 108, saphenous vein grafts 48, mean bypass grafts number 2.65/cases), and the mean period from CABG to TL was 41.6 +/- 34 days. The territories of stress induced ischemia were divided into 3 territories; left anterior descending (LAD), right coronary artery (RCA), and left circumflex (LCX) territories. Patency of the bypass grafts was estimated on the absence of transient perfusion defect (TPD) on TL images. The incidence of false positive results was higher in Dipyridamole TL (38%) than in Exercise TL (18%) and higher in LAD territories (38%) than in RCA (11%) and LCX (13%) territories. All false positive cases showed no evidence of chest pain and significant ST-T change during stress TL test. High incidence of false positive results of stress TL test was observed for the evaluation of artery bypass graft patency after CABG.
我们在冠状动脉旁路移植术(CABG)后评估动脉旁路移植血管通畅性时,经常遇到应力铊-201心肌闪烁显像(TL)出现假阳性结果的情况。本研究的目的是阐明这一发现的发生率及其临床意义。对62例CABG术后接受冠状动脉造影(CAG)的患者进行了研究。这些患者共进行了156次旁路移植(动脉移植物108例,大隐静脉移植物48例,平均每例旁路移植物数量2.65个),从CABG到TL的平均时间为41.6±34天。应激诱发缺血的区域分为3个区域:左前降支(LAD)、右冠状动脉(RCA)和左旋支(LCX)区域。根据TL图像上有无短暂灌注缺损(TPD)来评估旁路移植物的通畅性。双嘧达莫TL的假阳性结果发生率(38%)高于运动TL(18%),LAD区域(38%)高于RCA(11%)和LCX(13%)区域。所有假阳性病例在应激TL试验期间均无胸痛和明显ST-T改变的证据。在评估CABG术后动脉旁路移植血管通畅性时,观察到应激TL试验假阳性结果的发生率较高。