Nashitz J E, Rosner I, Rozenbaum M, Elias N, Yeshurun D
Department of Internal Medicine A, Bnai Zion Medical Center, Haifa, Israel.
Semin Arthritis Rheum. 1995 Feb;24(4):231-41. doi: 10.1016/s0049-0172(95)80033-6.
Interest in the rheumatologic manifestations of cancer is related in part to practical considerations, ie, earlier cancer diagnosis is possible through enhanced awareness of cancer-associated rheumatic syndromes. The spectrum of rheumatic disorders associated with cancer includes over 30 conditions, including hypertrophic osteoarthropathy, polymyalgia rheumatica, palmar fasciitis with polyarthritis, most autoimmune connective tissue diseases, and the more recently described antiphospholipid syndrome. It is generally held that extensive search for occult malignancy in most rheumatologic disorders is not cost efficient and not recommended unless accompanied by specific findings suggestive of malignancy. The present article discusses the supplementary findings that may justify malignancy evaluation.
对癌症的风湿性表现的关注部分与实际考虑因素有关，即通过提高对癌症相关风湿综合征的认识可以实现更早的癌症诊断。与癌症相关的风湿性疾病谱包括30多种病症，包括肥大性骨关节病、风湿性多肌痛、伴有多关节炎的掌腱膜炎、大多数自身免疫性结缔组织病以及最近描述的抗磷脂综合征。一般认为，在大多数风湿性疾病中广泛寻找隐匿性恶性肿瘤不符合成本效益，除非伴有提示恶性肿瘤的特定发现，否则不建议这样做。本文讨论了可能证明有必要进行恶性肿瘤评估的补充发现。
