Czeczot H
Department of Biochemistry, Medical School, Warszawa.
Acta Microbiol Pol. 1994;43(3-4):291-5.
The alkylation of bacterial DNA by two flavonoids: rhamnetin and isorhamnetin was examined using of strains Escherichia coli K-12: AB1157 (ada+) and (ada3). Rhamnetin and isorhamnetin and their putative metabolites formed in the presence of the S9 mix did not alkylate DNA at 0-6 of guanine.
利用大肠杆菌K-12菌株AB1157(ada+)和(ada3)研究了两种黄酮类化合物鼠李素和异鼠李素对细菌DNA的烷基化作用。在S9混合物存在的情况下形成的鼠李素、异鼠李素及其假定代谢产物在鸟嘌呤的0-6位均未使DNA烷基化。