• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

The transcriptional regulation of the preproenkephalin gene.

作者信息

Weisinger G

机构信息

Faculty of Medicine, Technion, Haifa, Israel.

出版信息

Biochem J. 1995 May 1;307 ( Pt 3)(Pt 3):617-29. doi: 10.1042/bj3070617.

DOI:10.1042/bj3070617
PMID:7741689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1136696/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/1b03aba34810/biochemj00064-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/f3dc703028a5/biochemj00064-0012-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/92dbdfcf62e9/biochemj00064-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/d3f6739f0755/biochemj00064-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/1b03aba34810/biochemj00064-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/f3dc703028a5/biochemj00064-0012-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/92dbdfcf62e9/biochemj00064-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/d3f6739f0755/biochemj00064-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0adc/1136696/1b03aba34810/biochemj00064-0017-a.jpg

相似文献

1
The transcriptional regulation of the preproenkephalin gene.前脑啡肽原基因的转录调控
Biochem J. 1995 May 1;307 ( Pt 3)(Pt 3):617-29. doi: 10.1042/bj3070617.
2
Molecular cloning and sequence determination of rat preproenkephalin cDNA: sensitive probe for studying transcriptional changes in rat tissues.大鼠前脑啡肽原cDNA的分子克隆与序列测定:用于研究大鼠组织转录变化的灵敏探针。
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7651-5. doi: 10.1073/pnas.81.23.7651.
3
Primary sequence of -1436 to +53 bp of the rat preproenkephalin gene putative Z-DNA and regulatory motifs.
Biochim Biophys Acta. 1992 Jul 15;1131(3):349-51. doi: 10.1016/0167-4781(92)90040-7.
4
Mechanisms underlying synaptic regulation of proenkephalin transcription.脑啡肽原转录的突触调节潜在机制。
NIDA Res Monogr. 1991;111:149-70.
5
Isolation and structural organization of the human preproenkephalin B gene.
Nature. 1983;306(5943):611-4. doi: 10.1038/306611a0.
6
Transgenic mice: preproenkephalin and the mu opiate receptor.
Ann N Y Acad Sci. 1996 Mar 22;780:19-28. doi: 10.1111/j.1749-6632.1996.tb15108.x.
7
Partial down-regulation at post-transcriptional level of the gene expression for preproenkephalin in the superior cervical ganglion of the maturing rat.成熟大鼠颈上神经节中前脑啡肽原基因表达在转录后水平的部分下调。
Brain Res Dev Brain Res. 1991 Mar 18;59(1):113-6. doi: 10.1016/0165-3806(91)90037-j.
8
[Structure and regulation of the expression of proenkephalin A and B genes and processing of the precursors].[脑啡肽原A和B基因的结构、表达调控及前体加工]
Nihon Rinsho. 1989 Oct;47(10):2181-6.
9
The structure and expression of the preproenkephalin gene.前脑啡肽原基因的结构与表达
Nucleic Acids Res. 1982 Dec 20;10(24):7905-18. doi: 10.1093/nar/10.24.7905.
10
Sequence similarity between opioid peptide precursors and DNA-binding proteins.
FEBS Lett. 1991 Apr 22;282(1):175-7. doi: 10.1016/0014-5793(91)80471-e.

引用本文的文献

1
Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward.多巴胺 D2 受体双向调节纹状体脑啡肽表达:可卡因奖赏的意义。
Cell Rep. 2022 Sep 27;40(13):111440. doi: 10.1016/j.celrep.2022.111440.
2
Immunomodulatory Role of Neuropeptides in the Cornea.神经肽在角膜中的免疫调节作用。
Biomedicines. 2022 Aug 16;10(8):1985. doi: 10.3390/biomedicines10081985.
3
Distribution of methionine and leucine enkephalin neurons within the social behavior circuitry of the male Syrian hamster brain.

本文引用的文献

1
Uptake of catecholamines by a particulate fraction of the adrenal medulla.肾上腺髓质微粒体部分对儿茶酚胺的摄取
J Biol Chem. 1962 Jul;237:2311-7.
2
Cholinergic regulation of rat preproenkephalin RNA in the adrenal medulla.
Brain Res Mol Brain Res. 1993 Apr;18(1-2):133-40. doi: 10.1016/0169-328x(93)90182-o.
3
Developmental changes in rat adrenal enkephalin precursor: peptide ratio.
Brain Res Dev Brain Res. 1993 Jan 15;71(1):75-80. doi: 10.1016/0165-3806(93)90107-l.
4
甲硫氨酸脑啡肽和亮氨酸脑啡肽神经元在雄性叙利亚仓鼠脑社会行为神经回路中的分布。
Brain Res. 2004 Dec 24;1030(1):28-48. doi: 10.1016/j.brainres.2004.09.034.
4
Stimulation of GABAB receptors increases the expression of the proenkephalin gene in slice cultures of rat neocortex.刺激GABAB受体可增加大鼠新皮质脑片培养物中前脑啡肽原基因的表达。
Naunyn Schmiedebergs Arch Pharmacol. 2003 Jun;367(6):640-7. doi: 10.1007/s00210-003-0746-z. Epub 2003 May 6.
5
Elevated proenkephalin-derived peptide levels in ACTH-producing adenomas: nucleus and cytoplasm localization.促肾上腺皮质激素分泌腺瘤中脑啡肽原衍生肽水平升高:细胞核与细胞质定位
Endocrine. 1998 Jun;8(3):231-40. doi: 10.1385/ENDO:8:3:231.
6
Widespread expression and estrogen regulation of PPEIA-3' nuclear RNA in the rat brain.大鼠脑中PPEIA - 3'核RNA的广泛表达及雌激素调节
Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):14037-41. doi: 10.1073/pnas.94.25.14037.
7
Maternal cocaine treatment alters dynorphin and enkephalin mRNA expression in brains of fetal rhesus macaques.母体可卡因治疗会改变恒河猴胎儿大脑中强啡肽和脑啡肽的mRNA表达。
J Neurosci. 1997 Feb 1;17(3):1112-21. doi: 10.1523/JNEUROSCI.17-03-01112.1997.
8
Regulation of the expression of the proenkephalin gene in cultured meningeal fibroblasts: opposite effects of alpha 1- and beta 2-adrenoceptors.原脑啡肽基因在培养的脑膜成纤维细胞中表达的调控:α1 -和β2 -肾上腺素能受体的相反作用
Naunyn Schmiedebergs Arch Pharmacol. 1996 Oct;354(4):404-10. doi: 10.1007/BF00168429.
cis-acting elements in the 5'-untranslated region of rat testis proenkephalin mRNA regulate translation of the precursor protein.
J Biol Chem. 1993 Oct 15;268(29):22164-9.
5
Immunodetection of endogenous opioid peptides in human brain tumors and associated cyst fluids.人脑肿瘤及相关囊液中内源性阿片肽的免疫检测。
Cancer Res. 1993 Oct 1;53(19):4715-9.
6
Cell-specific expression of preproenkephalin intronic heteronuclear RNA in the rat forebrain.
Brain Res Mol Brain Res. 1993 Jul;19(1-2):22-30. doi: 10.1016/0169-328x(93)90144-e.
7
The cAMP-response-element-binding protein interacts, but Fos protein does not interact, with the proenkephalin enhancer in rat striatum.环磷酸腺苷反应元件结合蛋白与大鼠纹状体中脑啡肽原增强子相互作用,而Fos蛋白则不与之相互作用。
Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7005-9. doi: 10.1073/pnas.90.15.7005.
8
Cloning and characterization of hamster proenkephalin gene.仓鼠前脑啡肽原基因的克隆与特性分析
DNA Cell Biol. 1994 Jan;13(1):25-35. doi: 10.1089/dna.1994.13.25.
9
Lipopolysaccharide induces proenkephalin gene expression in rat lymph nodes and adrenal glands.脂多糖诱导大鼠淋巴结和肾上腺中脑啡肽原基因的表达。
Endocrinology. 1994 Jan;134(1):475-81. doi: 10.1210/endo.134.1.8275961.
10
Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress.应激诱导前脑啡肽原基因调控的分子机制:CREB与小鼠下丘脑前脑啡肽原基因相互作用,并在高渗应激反应中发生磷酸化。
Mol Endocrinol. 1994 Feb;8(2):240-8. doi: 10.1210/mend.8.2.8170480.