Kutas L M, Duggan J M, Kauffman C A
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, USA.
Clin Infect Dis. 1995 Feb;20(2):286-90. doi: 10.1093/clinids/20.2.286.
Vertebral osteomyelitis is an unusual complication of pneumococcal infection. This report describes a patient who presented with back pain and lower extremity weakness after bacteremic pneumococcal pneumonia. Magnetic resonance imaging showed destruction of the L-4-L-5 vertebral bodies and thecal sac compression, and Streptococcus pneumoniae was isolated from an aspirate of the disk space. We found only 10 other cases of pneumococcal vertebral osteomyelitis in a review of the literature. In these 11 cases the presentations were usually subacute, and the onset of back pain was insidious. Elevated erythrocyte sedimentation rates were commonly noted. Computed tomography and magnetic resonance imaging were most helpful in delineating the extent of involvement in patients seen in the last decade. Successful treatment included surgery alone in 2 cases that occurred before the antibiotic era, surgery plus 6 weeks of antibiotic therapy in 1, and antibiotics alone for 4 weeks to 7 months in 5. Two patients seen in the preantibiotic era died.
脊柱骨髓炎是肺炎球菌感染的一种罕见并发症。本报告描述了一名患者,其在菌血症性肺炎球菌肺炎后出现背痛和下肢无力。磁共振成像显示L4-L5椎体破坏和硬脊膜囊受压,从椎间盘间隙抽吸物中分离出肺炎链球菌。在文献回顾中,我们仅发现另外10例肺炎球菌性脊柱骨髓炎病例。在这11例病例中,临床表现通常为亚急性,背痛起病隐匿。通常可见红细胞沉降率升高。计算机断层扫描和磁共振成像对确定过去十年中所见患者的受累范围最有帮助。成功的治疗包括:在抗生素时代之前发生的2例仅行手术治疗,1例手术加6周抗生素治疗,5例仅用抗生素治疗4周至7个月。在抗生素时代之前就诊的2例患者死亡。