George A E, Holodny A, Golomb J, de Leon M J
Department of Radiology, New York University Medical Center, New York, USA.
Neuroimaging Clin N Am. 1995 Feb;5(1):19-31.
This article summarizes the neuroradiology of Alzheimer's disease (AD) and details the radiologic features that permit the identification of patients with normal pressure hydrocephalus (NPH). Patients with presumed AD show a characteristic atrophy pattern with specific involvement of the temporal lobes and hippocampus. These findings have prognostic implications. Patients with NPH typically show severe motoric and gait deficits and initially mild cognitive impairment. Marked improvement is shown in select patients after ventricular shunting.
本文总结了阿尔茨海默病（AD）的神经放射学，并详细阐述了有助于识别正常压力脑积水（NPH）患者的放射学特征。疑似AD患者表现出特征性的萎缩模式，颞叶和海马体有特定受累。这些发现具有预后意义。NPH患者通常表现出严重的运动和步态缺陷，最初有轻度认知障碍。部分患者在进行脑室分流术后显示出明显改善。
