Bétrémieux P, Tréguier C, Pladys P, Bourdinière J, Leclech G, Lefrancois C
Paediatric Intensive Care Unit, Rennes Teaching Hospital, France.
Arch Dis Child Fetal Neonatal Ed. 1995 Jan;72(1):F3-7. doi: 10.1136/fn.72.1.f3.
Between 1988 and 1992, 18 mechanically ventilated newborn babies (mean weight 1300 g and gestational age 30 weeks) presented with deteriorating respiratory failure at a mean age of 29 days. All developed increased oxygen requirements, hypoxic and hypercapnic episodes, and radiological changes of fixed lobar emphysema or recurrent atelectasis which sometimes changed sides from one day to another. Tracheobronchography with iopydol-iopydone was normal in five (27%) cases, but in 13 showed tracheobronchial stenosis localised to the lower trachea (seven cases), to the right main bronchus (three cases), or including the left main bronchus (four cases). Eleven of these 13 patients underwent endoscopy and balloon dilatation of the stenotic area. Five patients died, one before endoscopy, one immediately after endoscopies, and three subsequently with severe bronchopulmonary dysplasia. The other six babies recovered without any sequelae after balloon dilatation.
1988年至1992年间，18名接受机械通气的新生儿（平均体重1300克，胎龄30周）在平均29日龄时出现呼吸衰竭恶化。所有患儿均出现吸氧需求增加、低氧血症和高碳酸血症发作，以及影像学上的固定性大叶性肺气肿或反复肺不张改变，有时一天内病变部位会发生改变。碘吡多醇-碘吡酮气管支气管造影显示，5例（27%）正常，但13例显示气管支气管狭窄，病变局限于下气管（7例）、右主支气管（3例）或累及左主支气管（4例）。这13例患者中的11例接受了内镜检查并对狭窄部位进行了球囊扩张。5例患者死亡，1例在内镜检查前死亡，1例在内镜检查后立即死亡，3例随后死于严重支气管肺发育不良。另外6名婴儿在球囊扩张后康复，无任何后遗症。
