Tan D T, Pullum K W, Buckley R J
Singapore National Eye Centre.
Cornea. 1995 Mar;14(2):130-7.
The indications and outcome of the wear of gas-permeable (GP) scleral contact lenses in 118 eyes of 85 patients attending a Scleral Contact Lens Clinic during a 5-year period from July 1988 to June 1993 were analysed. Ninety-nine eyes (83.9%) were originally fitted with PMMA lenses and were subsequently changed to GP lenses, whereas 19 (16.1%) were fitted with GP lenses from the outset. The mean duration of GP scleral lens wear was 15.3 months, with a range between 3 and 58 months. The indications for refitting the cases previously wearing PMMA scleral lenses with GP material were related to problems of chronic hypoxia. Thirty-three eyes (26.8%) had previous episodes of corneal oedema, and of the 27 that had a minimum of 3 months' follow-up, none experienced further episodes of oedema. Of the 32 eyes (26%) that had developed corneal vascularisation associated with PMMA scleral lens wear, two eyes were noted to have significant vessel regression after a period of GP wear, whereas in the remainder of cases, vessels remained static and nonprogressive. Thirty additional eyes (24.2%) experienced inadequate wear times associated with discomfort, and in these eyes the change to GP scleral lenses produced a statistically significant reduction in the inability to wear lenses beyond 4 h (p < 0.05).
对1988年7月至1993年6月期间在一家巩膜接触镜诊所就诊的85例患者的118只眼睛佩戴透气性（GP）巩膜接触镜的适应症和结果进行了分析。99只眼睛（83.9%）最初佩戴的是聚甲基丙烯酸甲酯（PMMA）镜片，随后更换为GP镜片，而19只眼睛（16.1%）从一开始就佩戴GP镜片。GP巩膜镜片的平均佩戴时间为15.3个月，范围在3至58个月之间。将之前佩戴PMMA巩膜镜片的病例改用GP材料的适应症与慢性缺氧问题有关。33只眼睛（26.8%）曾有角膜水肿发作，在至少随访3个月的27只眼睛中，没有一只眼睛再次出现水肿。在因佩戴PMMA巩膜镜片而出现角膜血管化的32只眼睛（26%）中，有两只眼睛在佩戴GP一段时间后出现了明显的血管消退，而在其余病例中，血管保持静止且无进展。另外30只眼睛（24.2%）因不适而佩戴时间不足，在这些眼睛中，更换为GP巩膜镜片后，佩戴镜片超过4小时的能力下降在统计学上有显著降低（p < 0.05）。
