Siebels M, Nöldge G, Sanwald R, Andrassy K
Medizinische Klinik, Universität Heidelberg.
Immun Infekt. 1995 Apr;23(2):60-1.
Classic polyarteritis nodosa is a necrotizing vasculitis affecting medium- and small-sized arteries. Renal involvement from aneurysm formation is common and can result in perirenal or intrarenal bleeding. The gold standard of diagnostic procedures is the arteriography. Treatment of choice is a combination of steroids and cyclophosphamide, but in the case of severe hemorrhage surgery is mandatory. Patients with PAN need at least 2 years of long-term therapy; repeated arteriography will establish the efficacy of therapy.
经典结节性多动脉炎是一种影响中小动脉的坏死性血管炎。因动脉瘤形成导致的肾脏受累很常见,可引起肾周或肾内出血。诊断程序的金标准是动脉造影。首选治疗方法是类固醇和环磷酰胺联合使用,但在严重出血的情况下,手术是必需的。结节性多动脉炎患者需要至少2年的长期治疗;重复动脉造影将确定治疗效果。