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带血管蒂游离腓骨移植治疗股骨头坏死。103例髋关节的长期随访研究。

Treatment of osteonecrosis of the femoral head with free vascularized fibular grafting. A long-term follow-up study of one hundred and three hips.

作者信息

Urbaniak J R, Coogan P G, Gunneson E B, Nunley J A

机构信息

Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

J Bone Joint Surg Am. 1995 May;77(5):681-94. doi: 10.2106/00004623-199505000-00004.

Abstract

The results for 103 consecutive hips (eighty-nine patients) that had been treated with free vascularized fibular grafting because of symptomatic osteonecrosis of the femoral head were reviewed in a prospective study. The disease was associated with consumption of alcohol in 30 percent of the hips, use of steroids in 17 percent, trauma in 13 percent, and Perthes disease in 3 percent; in the remaining 38 percent, the condition was idiopathic. All patients, except for one who died of unrelated causes 4.5 years after the operation, were followed for at least five years. By the time of the most recent follow-up evaluation, a total arthroplasty had been performed in thirty-one hips: two of the nineteen that were in stage II, according to the criteria of Marcus et al., at the time of the operation; five (23 percent) of the twenty-two that were in stage III; seventeen (43 percent) of the forty that were in stage IV; and seven (32 percent) of the twenty-two that were in stage V. Kaplan-Meier survivorship analyses demonstrated that the probability of conversion to a total hip arthroplasty within five years after free vascularized fibular grafting was 11 percent for the stage-II hips, 23 percent for the stage-III hips, 29 percent for the stage-IV hips, and 27 percent for the stage-V hips. There was a trend toward a lower rate of conversion to a total hip arthroplasty in patients who were less than thirty years old, but this difference did not reach significance (p = 0.06). No association was found between a causative factor and the probability of conversion to a total hip arthroplasty. The average Harris hip scores had improved at the latest follow-up evaluation, compared with the preoperative values (p < 0.001). For the stage-II hips, the average score improved from 56 to 80 points; for the stage-III hips, from 52 to 85 points; for the stage-IV hips, from 41 to 76 points; and for the stage-V hips, from 36 to 75 points. An outcome questionnaire, completed for 73 percent of the hips, revealed that 59 per cent of the hips that had not been subsequently treated with an arthroplasty did not limit or only slightly limited the patient's ability to carry out daily activities, and 62 percent did not limit or only slightly limited the patient's ability to work.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

对103例(89名患者)因股骨头症状性骨坏死接受游离血管化腓骨移植治疗的连续病例进行了前瞻性研究回顾。30%的病例与饮酒有关,17%与使用类固醇有关,13%与创伤有关,3%与佩吉特病有关;其余38%病因不明。除1例术后4.5年死于无关原因外,所有患者均随访至少5年。在最近一次随访评估时,31例髋关节已行全髋关节置换术:根据Marcus等人的标准,术中处于II期的19例中有2例;处于III期的22例中有5例(23%);处于IV期的40例中有17例(43%);处于V期的22例中有7例(32%)。Kaplan-Meier生存分析表明,游离血管化腓骨移植术后5年内转换为全髋关节置换术的概率,II期髋关节为11%,III期髋关节为23%,IV期髋关节为29%,V期髋关节为27%。年龄小于30岁的患者转换为全髋关节置换术的比例有降低趋势,但差异无统计学意义(p = 0.06)。未发现病因与转换为全髋关节置换术的概率之间存在关联。与术前值相比,最近一次随访评估时Harris髋关节平均评分有所改善(p < 0.001)。II期髋关节平均评分从56分提高到80分;III期髋关节从52分提高到85分;IV期髋关节从41分提高到76分;V期髋关节从36分提高到75分。对73%的髋关节完成的结果调查问卷显示,59%未随后行关节置换术的髋关节对患者进行日常活动的能力没有限制或仅有轻微限制,62%对患者的工作能力没有限制或仅有轻微限制。(摘要截选至400字)

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