Ward P A
Department of Pathology, University of Michigan Medical School, Ann Arbor, USA.
Hosp Pract (1995). 1995 May 15;30(5):35-41. doi: 10.1080/21548331.1995.11443197.
The understanding of cytokines is in its infancy, but it appears that overproduction or deficiency of these intracellular mediators may contribute to inflammatory and autoimmune diseases such as insulin-dependent diabetes mellitus and rheumatoid arthritis. As the complexities of cytokine actions and interactions are unraveled, therapeutic blockade or upregulation may be possible.