Thoron L, Arbit E
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
J Neurooncol. 1994;22(2):87-100. doi: 10.1007/BF01052885.
Abnormal hemostasis is a functional property of cancer. Hemostatic abnormalities are common in patients with systemic malignant disease and brain tumors. However, the incidence of thromboembolism is higher in patients with brain tumors than in those with systemic disease. This raises the question of whether or not hemostatic abnormalities found in the blood of the two groups of patients differs, suggesting different pathogeneses. The purpose of this report is to review abnormalities in blood and clinical manifestations of abnormal hemostasis found in brain tumors and cancer patients in an attempt to answer this question. Normal hemostasis, as currently understood, will be considered with an emphasis on features unique to the central nervous system.
异常止血是癌症的一种功能特性。止血异常在全身性恶性疾病和脑肿瘤患者中很常见。然而，脑肿瘤患者的血栓栓塞发生率高于全身性疾病患者。这就提出了一个问题，即两组患者血液中发现的止血异常是否不同，这表明发病机制不同。本报告的目的是回顾脑肿瘤和癌症患者血液中的异常以及异常止血的临床表现，试图回答这个问题。目前所理解的正常止血将在强调中枢神经系统独特特征的基础上进行讨论。
