Fujita M, Hosokawa M, Ohhara M, Shimizu Y
Department of Pathology, Sapporo National Hospital.
Rinsho Byori. 1995 Mar;43(3):211-20.
We studied 58 cases of mucosal carcinoma of the esophagus and 21 cases of submucosal carcinoma to evaluate the macroscopic features and histological risk factors (lymphatic and venous permeations and lymph node metastasis) by subclassification of depth of invasion (m1, m2, m3, sm1, sm2, sm3). Carcinoma of m1 and m2 invasion revealed neither venous permeation nor lymph node metastasis. One case of m2 carcinoma (5%) showed lymphatic permeation, 2 cases of m3 carcinomas (20%) showed lymphatic permeation and 3 cases (27%) had lymph node metastasis. Otherwise "sm" carcinoma revealed a high percentage of lymphatic permeation and lymph node metastasis. Also venous permeation were seen in some cases of "sm" carcinoma. The macroscopic appearance of all mucosal carcinomas was 0-II type and most of the 0-iib type carcinomas were "m1" carcinoma. Clinicopathologically it is useful to subclassify mucosal carcinoma as m1, m2, m3, and "m1" and "m2" carcinomas are indications for endoscopic mucosal resection.
我们研究了58例食管黏膜癌和21例黏膜下癌，通过对浸润深度（m1、m2、m3、sm1、sm2、sm3）进行亚分类，评估其大体特征和组织学危险因素（淋巴和静脉浸润以及淋巴结转移）。m1和m2浸润的癌既未显示静脉浸润也未显示淋巴结转移。1例m2癌（5%）显示淋巴浸润，2例m3癌（20%）显示淋巴浸润，3例（27%）有淋巴结转移。另外，“sm”癌显示出较高比例的淋巴浸润和淋巴结转移。在一些“sm”癌病例中也可见静脉浸润。所有黏膜癌的大体外观均为0-II型，大多数0-iib型癌为“m1”癌。从临床病理学角度来看，将黏膜癌亚分类为m1、m2、m3是有用的，“m1”和“m2”癌是内镜黏膜切除术的指征。
