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双手双合诊盆腔检查作为一种筛查测试有什么价值吗?

Is there any value in bimanual pelvic examination as a screening test.

作者信息

Grover S R, Quinn M A

机构信息

Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Carlton, VIC.

出版信息

Med J Aust. 1995 Apr 17;162(8):408-10.

PMID:7746172
Abstract

OBJECTIVES

To assess the place of bimanual pelvic examination as a routine procedure in healthy women.

METHODS

2623 healthy, asymptomatic volunteers (mean age, 51 years; range, 25-92 years) underwent pelvic examination as part of an ovarian cancer screening program. The presence of a bulky or fibroid uterus and adnexal abnormality was noted. Pelvic ultrasonography was used to investigate adnexal abnormalities and was also performed in all women with an elevated serum CA-125 antigen level (> 35 U/mL). Laparoscopy or laparotomy was performed as clinically indicated.

RESULTS

A bulky or fibroid uterus was detected in 12.9% of women. The prevalence of abnormal adnexal findings was 1.5%, with a positive predictive value for a subsequent diagnosis of benign adnexal abnormality of 22%. The specificity of vaginal examination for malignancy was 99.9%. No ovarian malignancies were identified at initial screening.

CONCLUSIONS

This "routine" procedure is undertaken in the belief that it serves a screening purpose. The detection of benign uterine abnormality is of no clear benefit as progression to malignancy is rare. Bimanual pelvic examination is of questionable value as a screening strategy in view of the low incidence of ovarian cancer in healthy women, and the relatively high prevalence (1.5%) of relatively unimportant adnexal abnormalities.

摘要

目的

评估双合诊盆腔检查作为健康女性常规检查项目的作用。

方法

2623名健康、无症状的志愿者(平均年龄51岁;范围25 - 92岁)作为卵巢癌筛查项目的一部分接受了盆腔检查。记录是否存在子宫增大或肌瘤以及附件异常情况。采用盆腔超声检查来调查附件异常情况,并且所有血清CA - 125抗原水平升高(> 35 U/mL)的女性也都进行了超声检查。根据临床指征进行腹腔镜检查或剖腹手术。

结果

12.9%的女性检测出子宫增大或有肌瘤。附件异常发现的患病率为1.5%,后续诊断为良性附件异常的阳性预测值为22%。阴道检查对恶性肿瘤的特异性为99.9%。初次筛查未发现卵巢恶性肿瘤。

结论

进行这项“常规”检查是基于其具有筛查作用的信念。鉴于子宫恶性进展罕见,检测出良性子宫异常并无明显益处。考虑到健康女性卵巢癌发病率较低,以及相对不重要的附件异常患病率相对较高(1.5%),双合诊盆腔检查作为一种筛查策略的价值存疑。

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