Sperling M R, Saykin A J, Roberts F D, French J A, O'Connor M J
Comprehensive Epilepsy Center, Graduate Hospital, Philadelphia, PA 19146, USA.
Neurology. 1995 May;45(5):970-7. doi: 10.1212/wnl.45.5.970.
We evaluated employment after temporal lobectomy for refractory epilepsy in 86 patients (3.5 to 8 years of follow-up). Seventy-three patients qualified for the work force before and after surgery. Unemployment rates declined after surgery (18 patients [25%] unemployed before surgery, eight patients [11%] unemployed after surgery), and underemployment also tended to diminish. Improvement in occupational status related strongly to the degree of postoperative seizure relief. Seizure-free patients fared better (no unemployment, little underemployment) than patients with some seizure-free years and some years with seizures after surgery, whose high underemployment level persisted. Patients with seizures in each year after surgery fared worst (despite reduced seizure frequency), with increased unemployment after surgery. Age at surgery also influenced vocational outcome in patients who were unemployed before surgery. Historical, educational, cognitive, and behavioral measures did not correlate with vocational outcome. Employment gains came slowly; unemployed patients took up to 6 years to obtain work after surgery. Of 13 students at the time of surgery, 11 have graduated and nine are now employed. We conclude that seizures play a large role in limiting employment, and that by alleviating seizures, temporal lobectomy improves employability in people with refractory epilepsy. Surgery thereby provides benefit to individuals with epilepsy by increasing financial independence and to society by reducing unemployment.
我们评估了86例接受颞叶切除术治疗难治性癫痫患者的就业情况(随访3.5至8年)。73例患者在手术前后符合劳动力标准。术后失业率下降(术前18例[25%]失业,术后8例[11%]失业),就业不足情况也趋于减少。职业状况的改善与术后癫痫缓解程度密切相关。术后无癫痫发作的患者情况较好(无失业,就业不足情况较少),而术后有几年无癫痫发作但也有几年有癫痫发作的患者,其就业不足程度较高且持续存在。术后每年都有癫痫发作的患者情况最差(尽管癫痫发作频率降低),术后失业率增加。手术时的年龄也影响术前失业患者的职业结局。病史、教育程度、认知和行为指标与职业结局无关。就业改善进展缓慢;失业患者术后长达6年才找到工作。手术时有13名学生,其中11名已毕业,9名目前已就业。我们得出结论,癫痫发作在限制就业方面起很大作用,通过缓解癫痫发作,颞叶切除术可提高难治性癫痫患者的就业能力。手术从而通过增加经济独立性为癫痫患者个人带来益处,并通过减少失业为社会带来益处。