McLafferty R B, Taylor L M, Moneta G L, Yeager R A, Edwards J M, Porter J M
Department of Surgery, Oregon Health Sciences University, Portland, USA.
Am J Surg. 1995 May;169(5):492-5. doi: 10.1016/S0002-9610(99)80202-5.
The axillofemoral bypass graft (AxFG) is increasingly accepted as treatment for lower extremity ischemia caused by aortoiliac occlusive disease in high-risk patients. The incidence of upper extremity (UE) thromboembolism caused by occlusion of an AxFG and the results of treatment form the basis for this report.
From 1984 to the present, all patients undergoing axillofemoral bypass grafting were followed up in a vascular registry. A standardized operative technique, using an externally supported 8-mm polytetrafluoroethylene graft, was used in performing 202 AxFGs in 182 patients. UE thromboembolism caused by occlusion of an AxFG was identified by retrospective patient record review.
Occlusion of an AxFG occurred in 20 patients. Fifteen patients (75%) underwent immediate revision of the occluded graft. Two patients (10%) developed UE thromboembolism simultaneous with graft occlusion. One of these patients had immediate revision of the graft, and 1 had brachial embolectomy only. This patient and 4 others (25%) had the occluded AxFG left in place. Four of these 5 patients (80%) developed UE thromboembolism at 26 days, 2 years, 5 years, and 7 years, respectively, after occlusion. Overall, six UE thromboembolic complications occurred in 5 patients.
UE thromboembolism represents a significant and specific complication of occluded AxFGs in our series (2.7% of patients, 25% of occluded grafts). It may be prudent to prophylactically detach the axillary portion of the graft and repair the axillary artery in patients who do not require immediate revision of an occluded AxFG.
腋股旁路移植术(AxFG)越来越多地被用作高危患者因主髂动脉闭塞性疾病导致下肢缺血的治疗方法。本报告以AxFG闭塞引起的上肢(UE)血栓栓塞发生率及治疗结果为依据。
自1984年至今,对所有接受腋股旁路移植术的患者在血管登记处进行随访。采用标准化手术技术,使用外部支撑的8毫米聚四氟乙烯移植物,为182例患者实施了202例AxFG手术。通过回顾性查阅患者病历确定由AxFG闭塞引起的UE血栓栓塞。
20例患者出现AxFG闭塞。15例患者(75%)对闭塞的移植物立即进行了翻修。2例患者(10%)在移植物闭塞的同时发生了UE血栓栓塞。其中1例患者对移植物立即进行了翻修,1例仅进行了肱动脉取栓术。该患者及其他4例患者(25%)的闭塞AxFG未作处理。这5例患者中有4例(80%)分别在闭塞后26天、2年、5年和7年发生了UE血栓栓塞。总体而言,5例患者共发生6例UE血栓栓塞并发症。
在我们的系列研究中,UE血栓栓塞是闭塞AxFG的一种重要且特殊的并发症(占患者的2.7%,占闭塞移植物的25%)。对于不需要立即翻修闭塞AxFG的患者,预防性地分离移植物的腋部并修复腋动脉可能是谨慎的做法。