Mishalani S H, Lones M A, Said J W
Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Arch Pathol Lab Med. 1995 May;119(5):467-70.
Thymic involvement is an important feature of human immunodeficiency virus-related disease in the pediatric population. The most common lesions are thymic involution or atrophy, thymitis (thymic lymphoid hyperplasia), and dysinvolution with loss of Hassall's corpuscles. We report a case of an unusual form of thymic enlargement in a human immunodeficiency virus-infected boy. In addition to lymphoid hyperplasia similar to that associated with human immunodeficiency virus infection in lymph nodes and other sites, the thymus was characterized by multilocular cysts with squamous epithelial lining (multilocular cystic lesion of the thymus).
胸腺受累是儿科人群中人类免疫缺陷病毒相关疾病的一个重要特征。最常见的病变是胸腺退化或萎缩、胸腺炎(胸腺淋巴样增生)以及哈氏小体缺失的发育异常。我们报告了一例人类免疫缺陷病毒感染男孩出现的一种不寻常形式的胸腺肿大病例。除了与淋巴结及其他部位人类免疫缺陷病毒感染相关的淋巴样增生外,该胸腺的特征为伴有鳞状上皮内衬的多房囊肿(胸腺多房囊性病变)。