Rubin L A, Geran A, Rose T H, Cohen H
Women's College Hospital, Toronto, Ontario, Canada.
Arthritis Rheum. 1995 May;38(5):710-4. doi: 10.1002/art.1780380521.
Pulmonary vasculitis is an uncommon complication of systemic lupus erythematosus (SLE), and has not been previously documented in pregnancy. This case report describes the rapidly fatal course of a pregnant SLE patient, whose terminal illness was manifested by severe pulmonary hypertension and unexpected autopsy findings of medium and large vessel vasculitis. The relationship of these unusual manifestations to other clinical and serologic features of SLE, as well as novel therapeutic options, are discussed.
肺血管炎是系统性红斑狼疮（SLE）的一种罕见并发症，此前在妊娠中尚无相关记录。本病例报告描述了一名患有SLE的孕妇的快速致命病程，其末期疾病表现为严重的肺动脉高压以及尸检意外发现的中、大血管血管炎。文中讨论了这些异常表现与SLE的其他临床和血清学特征的关系，以及新的治疗选择。
