腺苷介导乙醇对环磷酸腺苷信号转导系统的作用。
Adenosine mediates the effects of ethanol on the cAMP signal transduction system.
作者信息
Gordon A S, Diamond I
机构信息
Department of Neurology, University of California, San Francisco 94110, USA.
出版信息
Alcohol Alcohol Suppl. 1993;2:437-41.
PMID:7748335
Abstract
Acute exposure to ethanol causes increased cAMP production whereas chronic exposure results in heterologous desensitization. These changes are due to accumulation of extracellular adenosine resulting from inhibition of adenosine uptake into cells.
摘要
急性乙醇暴露会导致环磷酸腺苷（cAMP）生成增加，而慢性暴露则会导致异源脱敏。这些变化是由于细胞对腺苷摄取的抑制导致细胞外腺苷积累所致。
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