Kong M S, Wang K L, Wong H F
Department of Pediatrics, Chang Gung Medical College, Taoyuan Hsien, Taiwan, R.O.C.
J Formos Med Assoc. 1994 Oct;93(10):885-7.
From October 1989 to March 1994, 30 endoscopic injection sclerotherapies were performed in four consecutive female children who had extrahepatic portal vein obstruction complicated with esophageal variceal bleeding. Eradication of varices was achieved in three patients. However, bleeding occurred again in two of these patients due to esophageal varix recurrence. One patient, who discontinued sclerotherapy because of hemoptysis during treatment, also had 12 episodes of esophageal bleeding which were controlled by shunt therapy. In addition to hemoptysis, other complications were bleeding during sclerotherapy and fever. The sclerotherapy complication rate in this study was 17%. Our results suggest that endoscopic injection sclerotherapy is an effective and safe method for the prevention of variceal bleeding in children with extrahepatic portal vein obstruction. Long-term regular endoscopy follow-up and even repeated sclerotherapy are needed to prevent bleeding due to recurrence of esophageal varices.
1989年10月至1994年3月，对4例连续性患有肝外门静脉阻塞并伴有食管静脉曲张出血的女童进行了30次内镜注射硬化疗法。3例患者的静脉曲张得以消除。然而，其中2例患者因食管静脉曲张复发再次出血。1例患者在治疗期间因咯血停止硬化疗法，也有12次食管出血发作，通过分流疗法得以控制。除咯血外，其他并发症包括硬化疗法期间出血和发热。本研究中硬化疗法的并发症发生率为17%。我们的结果表明，内镜注射硬化疗法是预防肝外门静脉阻塞患儿静脉曲张出血的一种有效且安全的方法。需要长期定期进行内镜随访，甚至重复硬化疗法，以预防因食管静脉曲张复发导致的出血。
