Futrell N
Department of Neurology, Medical College of Ohio, Toledo, USA.
Curr Opin Neurol. 1995 Feb;8(1):55-61.
Recent advances in understanding the role of inflammatory vascular disorders in the production of ischemic stroke have resulted in improved diagnosis and treatment of this subset of stroke patients. These disorders include collagen vascular diseases, the primary anti-phospholipid antibody syndrome and vasculitic diseases. However, the interest generated in this area has led to an overdiagnosis of vasculitis in stroke patients, some overuse of steroids, and the routine ordering of expensive laboratory tests which do not contribute to the evaluation and treatment of most cases of stroke. Inflammatory vascular disorders are reviewed in relation to the potential mechanisms of ischemic stroke, along with specific diagnostic and therapeutic considerations. The appropriate use of specialized laboratory tests and diagnostic pitfalls are also reviewed.
在理解炎症性血管疾病在缺血性卒中发生过程中的作用方面的最新进展，已使这类卒中患者的诊断和治疗得到改善。这些疾病包括胶原血管病、原发性抗磷脂抗体综合征和血管炎疾病。然而，该领域引发的关注导致了卒中患者血管炎的过度诊断、类固醇的一些过度使用，以及常规开具对大多数卒中病例的评估和治疗并无帮助的昂贵实验室检查。本文就炎症性血管疾病与缺血性卒中的潜在机制、特定的诊断和治疗考量进行综述。还对专门实验室检查的合理应用及诊断陷阱进行了综述。
