Maingi M, Glynn M F, Scully H E, Graham A F, Floras J S
Department of Medicine, University of Toronto, Ontario.
Can J Cardiol. 1995 May;11(5):429-32.
A 59-year-old male with a mechanical aortic valve taking warfarin presented to hospital with Brown-Séquard syndrome caused by a spontaneous spinal epidural hematoma (SSEH) precipitated by a coughing fit. Guided by a literature review of the risks of administering or withholding anticoagulation in this patient, doctors advised a regimen of warfarin to achieve an international normalized ratio of 1.5 to 2 and dipyridamole (75 mg qid) to protect against thromboembolic complications while minimizing the risk of recurrent SSEH.
一名59岁男性，植入机械主动脉瓣并服用华法林，因咳嗽引发自发性脊髓硬膜外血肿（SSEH）导致布朗 - 塞卡尔综合征而入院。在查阅关于该患者使用或停用抗凝剂风险的文献后，医生建议采用华法林治疗方案，使国际标准化比值达到1.5至2，并使用双嘧达莫（每日四次，每次75毫克），以预防血栓栓塞并发症，同时将复发性SSEH的风险降至最低。
