Milanov I, Georgiev D
Medical University Hospital, III Neurological Clinic, Sofia, Bulgaria.
Can J Neurol Sci. 1995 Feb;22(1):59-61. doi: 10.1017/s0317167100040531.
Writer's cramp is frequently associated with hand tremor and with other focal dystonias. Sometimes brain infarction, haemorrhage, arterio-venous malformations or tumors are found to cause symptomatic focal dystonias. A 44-year-old man came to our attention due to writer's cramp of his right hand and postural 6-8 Hz tremor. About three months after the onset of the disease the tremor and dystonia disappeared, while a right hemiparesis gradually appeared. Cranial computed tomography showed a hypodense nonhomogeneous lesion in the left cerebral hemisphere parietally, that was assumed to represent a cystic tumor. The patient underwent craniotomy and the histological diagnosis revealed an astrocytoma (Grade II-III). In conclusion our findings confirm the common anatomical basis of symptomatic focal dystonia and tremor. Both can appear after disruption of the pathways within and adjacent to the basal ganglia.
书写痉挛常与手部震颤及其他局限性肌张力障碍相关。有时会发现脑梗死、脑出血、动静脉畸形或肿瘤可导致症状性局限性肌张力障碍。一名44岁男性因右手书写痉挛及姿势性6 - 8Hz震颤前来就诊。在疾病发作约三个月后，震颤和肌张力障碍消失，同时逐渐出现右侧偏瘫。头颅计算机断层扫描显示左侧大脑半球顶叶有一个低密度不均匀病变，推测为囊性肿瘤。该患者接受了开颅手术，组织学诊断为星形细胞瘤（II - III级）。总之，我们的研究结果证实了症状性局限性肌张力障碍和震颤的共同解剖学基础。两者都可能在基底神经节内部及相邻通路中断后出现。
