Froum S J, Ortiz M, Witkin R T, Thaler R, Scopp I W, Stahl S S
J Periodontol. 1976 May;47(5):287-94. doi: 10.1902/jop.1976.47.5.287.
A clinical investigation was undertaken to compare regeneration of osseous defects following either osseous coagulum-bone blend grafts or open debridement procedures. Seventy-five sites in 28 patients were treated by the two procedures. The average fill in the 37 intraosseous defects treated by graft procedures (initial average depth = 4.22 mm, S.D. 1.73) was 2.98 mm, S.D. 1.44. The average fill in the 38 intraosseous lesions treated by open debridement procedure (initial average depth = 3.03 mm, S.D.0.80) was 0.66 mm, S.D. 0.80. Statistical analysis showed a significant difference (P greater than 0.01) in fill patterns between the bone blend and open debridement responses in favor of graft treated sites. Therefore greater levels of osseous regeneration apparently took place in our cases following osseous coagulum-bone blend autogenous graft procedures than following open debridement procedures in all types of defects studies.
进行了一项临床研究,以比较骨凝块-骨混合移植或开放清创术后骨缺损的再生情况。28例患者的75个部位接受了这两种手术治疗。采用移植手术治疗的37个骨内缺损(初始平均深度=4.22mm,标准差1.73)的平均填充量为2.98mm,标准差1.44。采用开放清创术治疗的38个骨内病变(初始平均深度=3.03mm,标准差0.80)的平均填充量为0.66mm,标准差0.80。统计分析表明,骨混合移植和开放清创术在填充模式上存在显著差异(P大于0.01),有利于移植治疗的部位。因此,在我们的病例中,在所有类型的缺损研究中,骨凝块-骨混合自体移植术后的骨再生水平明显高于开放清创术后。