Fujita H, Soga T, Suzuki J, Ishigatsubo Y, Mohri H, Okubo T, Nagashima Y, Misugi K
First Department of Internal Medicine, Yokohama City University School of Medicine.
Kansenshogaku Zasshi. 1995 Apr;69(4):398-403. doi: 10.11150/kansenshogakuzasshi1970.69.398.
To describe the clinico-pathological aspect of HIV/AIDS inpatients, we reviewed HIV/AIDS inpatients in our hospital since 1988. We evaluated risk factors, CD4 counts, CD4/8 ratio, cause of death and the survival time after diagnosis of AIDS. A total of 13 HIV sero-positive subjects were admitted to our hospital, including 11 cases (85%) with AIDS. One patient was a foreigner. All cases were male; age range 18-70 years. Hemophiliacs and sexually transmitted patients account for 62% and 38% of cases, respectively. There were no cases of intravenous drug users. In all cases with AIDS, CD4+ cells and CD4/8 ratio significantly decreased with median value of 73/microns and 0.18, respectively. Six cases (54%) were decreased and autopsy were done in four cases. Findings of autopsy revealed HIV encephalopathy and systemic various infection, including Pneumocystis carinii, cytomegalovirus, papilloma virus and pox virus. Cytomegalovirus infection was found in all cases; one had innumerable inclusion bodies in lung, adrenal gland and intestines. The median survival time after diagnosis of AIDS were 26 months.
为描述艾滋病病毒/艾滋病（HIV/AIDS）住院患者的临床病理特征，我们回顾了自1988年以来我院收治的HIV/AIDS住院患者情况。我们评估了危险因素、CD4细胞计数、CD4/8比值、死亡原因以及艾滋病确诊后的生存时间。我院共收治了13例HIV血清学阳性患者，其中11例（85%）为艾滋病患者。1例患者为外国人。所有病例均为男性，年龄在18至70岁之间。血友病患者和性传播感染患者分别占病例总数的62%和38%。无静脉吸毒者病例。在所有艾滋病病例中，CD4 + 细胞和CD4/8比值显著降低，中位数分别为73/微升和0.18。6例（54%）病情恶化，4例进行了尸检。尸检结果显示存在HIV脑病和全身性各种感染，包括卡氏肺孢子虫、巨细胞病毒、乳头瘤病毒和痘病毒。所有病例均发现巨细胞病毒感染；1例在肺、肾上腺和肠道中有无数包涵体。艾滋病确诊后的中位生存时间为26个月。
