皮质类固醇对获得性免疫缺陷综合征合并卡氏肺孢子虫相关呼吸衰竭儿童生存情况的影响。
Effect of corticosteroids on survival of children with acquired immunodeficiency syndrome and Pneumocystis carinii-related respiratory failure.
作者信息
McLaughlin G E, Virdee S S, Schleien C L, Holzman B H, Scott G B
机构信息
Department of Pediatrics, University of Miami School of Medicine, Florida 33101, USA.
出版信息
J Pediatr. 1995 May;126(5 Pt 1):821-4. doi: 10.1016/s0022-3476(95)70421-3.
The medical records of patients with acquired immunodeficiency syndrome were reviewed to evaluate the effect of our adoption to the pediatric population of the National Institutes of Health recommendation for adjunctive corticosteroid therapy in adults with Pneumocystis carinii pneumonia. In 21 episodes of P. carinii-related respiratory failure, only adjunctive corticosteroids were associated with a significant improvement in survival to successful removal of the tracheal tube, from a historical rate of 11% to 91%.
回顾获得性免疫缺陷综合征患者的病历，以评估我们采用美国国立卫生研究院针对成人卡氏肺孢子虫肺炎辅助性皮质类固醇疗法的建议应用于儿科人群的效果。在21例与卡氏肺孢子虫相关的呼吸衰竭病例中，仅辅助性皮质类固醇与气管插管成功拔除后的生存率显著提高相关，从历史上的11%提高到91%。
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