Takeuchi S, Irimajiri A
Department of Physiology, Kochi Medical School, Nankoku, Japan.
Jpn J Physiol. 1994;44 Suppl 2:S317-9.
The mechanisms underlying the marginal cells' ion transport and endocochlear potential (EP) generation are still controversial. Conductive pathways in the basolateral membrane of isolated strial marginal cells of the gerbil have been investigated by the patch-clamp technique. Two types of ion channel, 80 pS Cl- and 25 pS Ca(2+)-activated nonselective cation, were identified frequently. The abundance of these two channels as the conductive pathways for Na+, K+, and Cl- in the basolateral membrane must be taken into account when addressing the role of strial marginal cells in generating EP.
边缘细胞离子转运及内淋巴电位（EP）产生的潜在机制仍存在争议。采用膜片钳技术研究了沙鼠离体血管纹边缘细胞基底外侧膜的传导途径。经常鉴定出两种类型的离子通道，即80 pS的Cl-通道和25 pS的Ca(2+)激活的非选择性阳离子通道。在探讨血管纹边缘细胞在产生EP中的作用时，必须考虑这两种通道作为基底外侧膜中Na+、K+和Cl-传导途径的丰度。
