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[儿童和青少年大脑半球肿瘤。治疗结果、残留综合征和局灶性癫痫]

[Tumors of the cerebral hemispheres in children and adolescents. Results of treatment, residual syndromes and focal epilepsy].

作者信息

Haupt C, Zarbock G, Schulte F J

机构信息

Kinderklinik, Universitäts-Krankenhaus Hamburg Eppendorf.

出版信息

Klin Padiatr. 1995 Mar-Apr;207(2):73-80. doi: 10.1055/s-2008-1046515.

Abstract

Tumors of the cerebral hemispheres comprise a big variety of histologic tumor types. Therefore, in the literature usually only specific subgroups such as benign gliomas and temporal lobe tumors are reported. In this study we report on 44 tumors of the cerebral hemispheres, including 9 angiomas. Apart from the treatment results concerning event free survival, the neurological and neuropsychological outcome of the patients were assessed. A peculiarity in the hemispheric tumors is their association with focal epilepsies. In 94% of our patient series, epileptic seizures had been the first tumor associated symptom and approximately 62% developed focal epilepsy. Seizure types, their association with tumor location and histology, the success of tumor therapy in concern of the epilepsy and the significance of the electroencephalogram in the follow up care of these patients were assessed separately.

摘要

大脑半球肿瘤包含多种组织学肿瘤类型。因此,文献中通常仅报道特定亚组,如良性胶质瘤和颞叶肿瘤。在本研究中,我们报告了44例大脑半球肿瘤,其中包括9例血管瘤。除了无事件生存的治疗结果外,还评估了患者的神经和神经心理结局。半球肿瘤的一个特点是它们与局灶性癫痫有关。在我们的患者系列中,94%的患者癫痫发作是首个与肿瘤相关的症状,约62%的患者发展为局灶性癫痫。我们分别评估了癫痫发作类型、它们与肿瘤位置和组织学的关联、肿瘤治疗对癫痫的疗效以及脑电图在这些患者后续护理中的意义。

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