Yoshikawa T T, Norman D C
Office of Geriatrics and Extended Care, United States Department of Veterans Affairs, Washington, DC, USA.
Med Clin North Am. 1995 May;79(3):651-61. doi: 10.1016/s0025-7125(16)30061-x.
Infections are common in elderly persons. The clinical manifestations of infection may be atypical or absent in the elderly. The microbial cause for many common infections may be more diverse in elderly patients, and obtaining diagnostic clinical specimens often is more difficult. Aging is associated with changes in pharmacokinetics and a higher rate of adverse drug reactions. These factors impact on the approach to treating infections in the elderly.
感染在老年人中很常见。感染的临床表现在老年人中可能不典型或不存在。许多常见感染的微生物病因在老年患者中可能更多样化,而且获取诊断性临床标本往往更困难。衰老与药代动力学变化及较高的药物不良反应发生率相关。这些因素影响老年人感染的治疗方法。