Becher Klaus Friedrich, Klempien Ingo, Wiedemann Andreas
Abteilung Geriatrie und Frührehabilitation, HELIOS Hanseklinikum Stralsund, Große Parower Straße 47-54, 18437, Stralsund, Deutschland.
Abteilung für Klinische Hygiene und Infektiologie, HELIOS Hanseklinikum Stralsund, Große Parower Straße 47-54, 18437, Stralsund, Deutschland.
Z Gerontol Geriatr. 2015 Oct;48(7):588-94. doi: 10.1007/s00391-015-0947-3. Epub 2015 Aug 29.
Acute infection of the urinary tract is one of the most commonly encountered bacterial infections in the frail elderly population and is responsible for substantial morbidity and recurrent infections with antibiotic resistance. Although generally considered to be self-limiting without treatment or easily treated with a short antibiotic regime, urinary tract infections (UTIs) often have a dramatic history, associated with incomplete resolution and frequent recurrence. The biological complexity of the infections combined with a dramatic rise in antibiotic-resistant pathogens highlight the need for an anticipating strategy for therapy necessary for a rapid recovery. The first crucial step is the classification in asymptomatic bacteriuria or complicated pyelonephritis, on which the decision for the intensity of treatment and diagnostic effort is based. For the selection of empiric antibiotic therapy, knowledge about the predominant uropathogens as well as local resistance patterns is important. In this manner, most urinary tract infections in the elderly can be treated without greater expense.
急性尿路感染是体弱老年人群中最常见的细菌感染之一,会导致严重的发病率以及伴有抗生素耐药性的反复感染。尽管通常认为未经治疗的尿路感染是自限性的,或者通过短期抗生素治疗方案很容易治愈,但尿路感染往往有着复杂的病史,与未完全治愈和频繁复发有关。感染的生物学复杂性加上抗生素耐药病原体的急剧增加,凸显了制定快速康复所需的前瞻性治疗策略的必要性。第一步关键是将其分类为无症状菌尿或复杂性肾盂肾炎,这是决定治疗强度和诊断力度的基础。对于经验性抗生素治疗的选择,了解主要的尿路病原体以及当地的耐药模式很重要。通过这种方式,大多数老年尿路感染患者可以在不增加太多费用的情况下得到治疗。