Fung P A, Gaertig J, Gorovsky M A, Hallberg R L
Department of Biology, Syracuse University, NY 13244, USA.
Science. 1995 May 19;268(5213):1036-9. doi: 10.1126/science.7754381.
Thermotolerance is an inducible state that endows cells with an enhanced resistance to thermal killing. Heat shock proteins are believed, and in a few instances have been shown, to be the agents conferring this resistance. The role of a small cytoplasmic RNA (G8 RNA) in developing thermotolerance in Tetrahymena thermophila was investigated by creating a strain devoid of all functional G8 genes. These G8 null cells mounted an apparently normal heat shock response, but they were unable to establish thermotolerance.
