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[妊娠大鼠肝脏中的维生素D3代谢]

[Vitamin D3 metabolism in the liver of pregnant rats].

作者信息

Shirankova T G, Ivashkevich S P, Apukhovskaia L I

出版信息

Ukr Biokhim Zh (1978). 1994 May-Jun;66(3):28-33.

PMID:7754552
Abstract

The exchange of vitamin D3 in the liver of pregnant rats has been studied. Incorporation of (3H)-vitamin D3 into the liver of pregnant rats on the 13th and 21st day of pregnancy made up 85% and 90% respectively of the intensity of absorption of the summary label by controlled animals. It is found that the period of exchange of (3H)-cholecalciferol in these animals increases with prolongation of pregnancy. The 25-hydroxylation of vitamin D3 in the liver of rats on the 13th and 21st day of pregnancy significantly decreases and makes up 30% and 50% of its hydroxylation in the nonpregnant rats.

摘要

对妊娠大鼠肝脏中维生素D3的交换情况进行了研究。在妊娠第13天和第21天,(3H)-维生素D3在妊娠大鼠肝脏中的掺入量分别占对照动物总标记吸收强度的85%和90%。发现这些动物中(3H)-胆钙化醇的交换期随妊娠时间延长而增加。在妊娠第13天和第21天,大鼠肝脏中维生素D3的25-羟化显著降低,分别占未妊娠大鼠羟化量的30%和50%。

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