用³H维生素D3给药后怀孕和哺乳期母鼠体内的维生素D3硫酸共轭物

Vitamin D3 sulfoconjugate in pregnant and lactating mother rats after dosing with 3H vitamin D3.

作者信息

Le Boulch N, Gulat-Marnay C, Miravet L, Laromiquière M, Raoul Y

出版信息

Steroids. 1980 Jul;36(1):21-6. doi: 10.1016/0039-128x(80)90064-1.

Abstract

Twenty four hours after dosing of pregnant rats with 3H vitamin D3 i.v. the sulfoconjugate was detected only in the kidney. In contrast, 24 or 48 hours after 3H vitamin D3 i.v. dosing the vitamin D3 sulfoconjugate was detected in the plasma, liver, kidney and mammary glands of lactating mother rats.

摘要

给怀孕大鼠静脉注射³H维生素D3 24小时后，仅在肾脏中检测到硫酸结合物。相比之下，在静脉注射³H维生素D3 24或48小时后，在泌乳母鼠的血浆、肝脏、肾脏和乳腺中检测到维生素D3硫酸结合物。