Stroganova T A, Posikera I N, Sergienko E A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1995 Jan-Feb;45(1):66-77.
Late effects of early visual deprivation on state control in sleep were studied in 23 infants with bilateral congenital cataract before and after surgery (usually, on the 6th month of life). In the course of three years 67 observations were performed. Laboratory assessments included videotaping infant sleep behaviour, recording EEG, EOG, ECG, galvanic skin response. It was shown that the early visual deprivation led to general changes in the basic mechanisms underlying state control in infancy. The sleep stages (active and quiet sleep), their duration and physiological autonomic and central characteristics were modified as compared to the age norm over a protracted period after surgery, when the visual experience became available for the infant. This type of sleep cycle can be identified as "partially perinatal sleep pattern". Revealed peculiarities of sleep cycle organization were suggested to reflect the higher level of activation in the neural arousal systems owing to the deficit of environmental stimulation during the critical stage (2-4 months) of brain development.
对23例双侧先天性白内障婴儿在手术前后（通常在出生后第6个月）研究了早期视觉剥夺对睡眠状态控制的远期影响。在三年期间进行了67次观察。实验室评估包括录制婴儿睡眠行为的录像、记录脑电图、眼电图、心电图、皮肤电反应。结果表明，早期视觉剥夺导致婴儿期状态控制基础的基本机制发生总体变化。与年龄正常标准相比，在手术后很长一段时间内，当婴儿有视觉体验时，睡眠阶段（主动和安静睡眠）、其持续时间以及生理自主和中枢特征都发生了改变。这种睡眠周期类型可被确定为“部分围产期睡眠模式”。所揭示的睡眠周期组织特点被认为反映了在大脑发育关键阶段（2 - 4个月）由于环境刺激不足，神经唤醒系统中更高水平的激活。
