Van Bastelaere S, Quisthoudt P, Coene L, Jutten G, Vanderputte S, Cerckel L
Department of General Surgery, KLINA, Brasschaat, Belgium.
Acta Chir Belg. 1995 Mar-Apr;95(2):92-4.
Starting from a case report of a six-month-old boy with a hepatoblastoma, we discuss this topic. New virologic and cytogenetic findings in hepatoma are mentioned in the chapter "epidemiology". In "diagnosis" we focus on history, physical examination, echography, conventional RX, the role of CT-scan of abdomen and thorax, of fine needle aspiration, arteriography and magnetic resonance. In "therapy" we emphasize the new therapeutical means: chemotherapy, orthotopic liver transplantation, resection of pulmonary metastases, as well as radiotherapy and immunotargeting chemotherapy. We conclude that surgery still is the cornerstone of treatment, but the new therapeutical means create hopeful perspectives in outcome.
从一名患有肝母细胞瘤的六个月大男童的病例报告出发,我们来讨论这个话题。肝癌方面新的病毒学和细胞遗传学发现将在“流行病学”章节中提及。在“诊断”部分,我们重点关注病史、体格检查、超声检查、传统X线检查、腹部和胸部CT扫描的作用、细针穿刺活检、动脉造影以及磁共振成像。在“治疗”部分,我们着重介绍新的治疗方法:化疗、原位肝移植、肺转移灶切除术,以及放疗和免疫靶向化疗。我们得出结论,手术仍然是治疗的基石,但新的治疗方法为改善治疗效果带来了充满希望的前景。