痰液与黏液纤毛清除机制。
Sputum and mucociliary clearance mechanisms.
作者信息
Reid L
出版信息
Postgrad Med J. 1976 Apr;52(606):183-9. doi: 10.1136/pgmj.52.606.183.
Abstract
Bronchial secretion forms a periciliary liquid layer and may also give rise to thicker secretion that moves on the tips of the cilia. This latter material as collected at bronchoscopy or coughed up as sputum is a viscoelastic substance behaving in a characteristic way over a wide range of shear rates. The anatomical basis of secretion is described and its control as established by organ culture.
摘要
支气管分泌物形成纤毛周围液体层，也可能产生更浓稠的分泌物，这些分泌物在纤毛顶端移动。在支气管镜检查时收集的或作为痰液咳出的后一种物质是一种粘弹性物质，在很宽的剪切速率范围内表现出独特的行为。本文描述了分泌物的解剖学基础及其通过器官培养确定的调控机制。
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Sputum and mucociliary clearance mechanisms.痰液与黏液纤毛清除机制。
Postgrad Med J. 1976 Apr;52(606):183-9. doi: 10.1136/pgmj.52.606.183.
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本文引用的文献
1
The culture of mature organs in a synthetic medium.在合成培养基中对成熟器官进行培养。
Exp Cell Res. 1959 Jan;16(1):118-47. doi: 10.1016/0014-4827(59)90201-0.
2
Ultrastructure of cells in the human bronchial submucosal glands.人支气管黏膜下腺细胞的超微结构
J Anat. 1970 Sep;107(Pt 2):281-99.
3
The viscosity of bronchial secretion.
Clin Sci. 1970 Jan;38(1):145-56. doi: 10.1042/cs0380145.
4
A reconstruction of the duct system and secretory tubules of the human bronchial submucosal gland.人支气管黏膜下腺导管系统和分泌小管的重建
Thorax. 1969 Nov;24(6):729-36. doi: 10.1136/thx.24.6.729.
5
Mucus transport in the tracheobronchial tree of normal and bronchitic rats.正常大鼠和患支气管炎大鼠气管支气管树中的黏液运输
J Pathol. 1972 Feb;106(2):81-93. doi: 10.1002/path.1711060204.
6
Secretory activity of the human bronchial mucous glands in vitro.
Exp Mol Pathol. 1972 Jun;16(3):362-81. doi: 10.1016/0014-4800(72)90011-1.
7
Individual and group correlations of sputum viscosity and airways obstruction.痰液黏稠度与气道阻塞的个体及群体相关性。
Bull Physiopathol Respir (Nancy). 1973 Mar-Apr;9(2):339-47.
8
An organ culture study of the effect of drugs on the secretory activity of the human bronchial submucosal gland.药物对人支气管黏膜下腺分泌活性影响的器官培养研究
Clin Sci. 1972 Oct;43(4):533-43. doi: 10.1042/cs0430533.
9
The elasticity of sputum at low shear rates.低剪切速率下痰液的弹性
Biorheology. 1974 Nov;11(6):417-26. doi: 10.3233/bir-1974-11604.
10
The physical and chemical properties of bronchial secretion.支气管分泌物的物理和化学性质。
Br J Dis Chest. 1974 Oct;68:215-27. doi: 10.1016/0007-0971(74)90045-x.
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