精神分裂症患者在双耳融合词任务中右耳（左半球）优势较小。
Smaller right ear (left hemisphere) advantage for dichotic fused words in patients with schizophrenia.
作者信息
Bruder G, Rabinowicz E, Towey J, Brown A, Kaufmann C A, Amador X, Malaspina D, Gorman J M
机构信息
Department of Biopsychology, New York State Psychiatric Institute, NY 10032, USA.
出版信息
Am J Psychiatry. 1995 Jun;152(6):932-5. doi: 10.1176/ajp.152.6.932.
OBJECTIVE
The purposes of this study were to compare right ear (left hemisphere) advantage for dichotic words in schizophrenia and depression and to assess its association with antipsychotic medication, symptom ratings, and gender.
METHOD
Thirty-two schizophrenic patients and 65 patients with major depression were given the Fused Rhymed Words Test, a dichotic listening measure of hemispheric dominance for language.
RESULTS
An earlier finding of smaller left hemisphere advantage in schizophrenic patients was replicated. There was no significant change in ear advantage in a subgroup of the schizophrenic patients tested when they were taking neuroleptics and when they were not. The smaller left hemisphere advantage in the schizophrenic patients was not dependent on gender but was related to symptom ratings on the Positive and Negative Syndrome Scale.
CONCLUSIONS
The findings are consistent with a left hemisphere dysfunction in schizophrenia, which is associated with positive symptoms.
目的
本研究旨在比较精神分裂症患者和抑郁症患者在双耳分听单词时右耳（左半球）优势，并评估其与抗精神病药物、症状评分及性别的关联。
方法
对32名精神分裂症患者和65名重度抑郁症患者进行了融合押韵词测试，这是一种用于测量语言半球优势的双耳分听测试。
结果
重复了之前关于精神分裂症患者左半球优势较小的研究结果。在接受测试的精神分裂症患者亚组中，服用抗精神病药物时和未服用时，耳优势没有显著变化。精神分裂症患者较小的左半球优势不依赖于性别，但与阳性和阴性症状量表上的症状评分有关。
结论
这些发现与精神分裂症患者左半球功能障碍一致，且与阳性症状相关。
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