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印度中央邦拜加人的血清蛋白(GC、TF和PI亚型)的遗传变异。

Genetic variation of serum proteins (GC, TF and PI subtypes) in the Baigas of Madhya Pradesh, India.

作者信息

Reddy P H, Mastana S S

机构信息

Department of Obstetrics and Gynaecology, Faculty of Clinical Sciences, University College London, UK.

出版信息

Anthropol Anz. 1995 Mar;53(1):53-6.

PMID:7755374
Abstract

The distribution of group specific component (GC), transferrin (TF) and alpha-1-antitrypsin (PI) subtypes was determined by isoelectric focusing of plasma samples from 140 unrelated individuals belonging to the Baiga tribe of Madhya Pradesh, India. The allele frequencies observed for GC (GC1S = 0.6742, GC1F = 0.1326 and GC2 = 0.1932), TF (TFC1 = 0.7920, TFC2 = 0.1606, TFC3 = 0.0146 and TFD = 0.0328) and PI (PIM1 = 0.7179, PIM2 = 0.1750, PIM3 = 0.0893, PIS = 0.0107 and PIF = 0.0071) demonstrate appreciable heterogeneity of the Baigas compared to other populations of the region.

摘要

通过对来自印度中央邦拜加部落140名无亲缘关系个体的血浆样本进行等电聚焦,确定了群体特异性成分(GC)、转铁蛋白(TF)和α-1-抗胰蛋白酶(PI)亚型的分布。观察到的GC(GC1S = 0.6742,GC1F = 0.1326,GC2 = 0.1932)、TF(TFC1 = 0.7920,TFC2 = 0.1606,TFC3 = 0.0146,TFD = 0.0328)和PI(PIM1 = 0.7179,PIM2 = 0.1750,PIM3 = 0.0893,PIS = 0.0107,PIF = 0.0071)的等位基因频率表明,与该地区的其他人群相比,拜加人具有明显的异质性。

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