Hock F J
HOECHST AG, General Pharmacology Research, Pharmacological Screening, Frankfurt/M., Germany.
Behav Brain Res. 1995 Jan 23;66(1-2):143-50. doi: 10.1016/0166-4328(94)00135-3.
Pharmacological treatment strategies for the treatment in dementia disorders were described. A selection of the 15 different classes described by Fröstl and Maitre was made. In the paper there were included and described in detail the following classes: piracetam-type compounds, co-dergocrine-type compounds, vasodilators and haemorheological agents, cholinesterase inhibitors, ACTH and vasopressin analogs and angiotensin II and angiotensin converting enzyme inhibitors. Some compounds e.g. propentofylline, vincamine, THA and RA-octil were described in more detail.
文中描述了用于治疗痴呆症的药物治疗策略。从弗罗斯特尔和梅特尔所描述的15种不同类别中进行了选择。该论文详细纳入并描述了以下类别:吡拉西坦类化合物、麦角隐亭类化合物、血管扩张剂和血液流变学药物、胆碱酯酶抑制剂、促肾上腺皮质激素和血管加压素类似物以及血管紧张素II和血管紧张素转换酶抑制剂。一些化合物,如丙戊茶碱、长春胺、四氢氨基吖啶和RA-辛酯,进行了更详细的描述。