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放疗后二尖瓣后叶固定导致的严重二尖瓣反流

Severe mitral regurgitation caused by immobile posterior leaflet after radiotherapy.

作者信息

Jones R A, Hall R J, Fraser A G

机构信息

Department of Cardiology, University Hospital of Wales, Cardiff, United Kingdom.

出版信息

J Am Soc Echocardiogr. 1995 Mar-Apr;8(2):207-10. doi: 10.1016/s0894-7317(05)80409-2.

DOI:10.1016/s0894-7317(05)80409-2
PMID:7756005
Abstract

Radiotherapy may affect the heart in several ways. We describe a child who had pulmonary edema caused by severe mitral regurgitation after thoracic radiotherapy for a Ewing sarcoma. Transesophageal echocardiography demonstrated this to be caused by an immobilized posterior leaflet, and valve replacement was necessary. This is the first reported patient with rapid progression to severe valvar disease after radiotherapy and in whom this novel mechanism has been demonstrated.

摘要

放射治疗可能通过多种方式影响心脏。我们描述了一名儿童，其因尤因肉瘤接受胸部放射治疗后出现严重二尖瓣反流导致肺水肿。经食管超声心动图显示这是由后叶固定所致，因此需要进行瓣膜置换。这是首例报道的放疗后迅速进展为严重瓣膜疾病且证实有这种新机制的患者。

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