Merikallio E, Mattila S, Tala P
Scand J Thorac Cardiovasc Surg. 1976;10(1):63-76. doi: 10.3109/14017437609167770.
Heart transplantation was performed on 21 mongrel dogs using donor-circulation of another, bigger dog, instead of the heart-lung machine. All the dogs survived the operation. They showed a moderate metabolic acidosis, which was more related to a reduced blood flow of the recipient than to inadequate oxygenation capacity of the pump dog during transplantation, and which was corrected by administration of bicarbonate after the procedure. The technique was superior to disposable oxygenators in reducing the expense of the operation and providing a more gentle perfusion.
使用另一只体型更大的犬只的供体循环而非心肺机,对21只杂种犬进行了心脏移植手术。所有犬只均存活至术后。它们出现了中度代谢性酸中毒,这更多与受体血流减少有关,而非与移植过程中供血犬的氧合能力不足有关,术后通过给予碳酸氢盐得以纠正。该技术在降低手术费用和提供更温和的灌注方面优于一次性氧合器。